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Scavenger receptor BI and HDL regulate thymocyte apoptosis in sepsis

OBJECTIVE: Thymocyte apoptosis is a major event in sepsis; however, how this process is regulated remains poorly understood. APPROACH AND RESULTS: Septic stress induces glucocorticoids (GC) production which triggers thymocyte apoptosis. Here, we used scavenger receptor BI (SR-BI) null mice, which ar...

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Detalhes bibliográficos
Main Authors: Guo, Ling, Zheng, Zhong, Ai, Junting, Howatt, Deborah A., Mittelstadt, Paul R., Thacker, Seth, Daugherty, Alan, Ashwell, Jonathan D., Remaley, Alan T., Li, Xiang-An
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010389/
https://ncbi.nlm.nih.gov/pubmed/24603680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302484
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