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β-Asarone protects PC12 cells against OGD/R-induced injury via attenuating Beclin-1-dependent autophagy

AIM: To explore the effects of β-asarone from Acorus Tatarinowii Schott on autophagy in an ischemic stroke model of PC12 cells. METHODS: The ischemic stroke model of PC12 cells was made by OGD/R (2 h oxygen-glucose deprivation followed by 24 h reperfusion). Drug administration was started 1 h before...

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Detalhes bibliográficos
Main Authors: Mo, Zhen-tao, Fang, Yong-qi, He, Yu-ping, Zhang, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010377/
https://ncbi.nlm.nih.gov/pubmed/22543703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.35
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