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E-cadherin promotes proliferation of human ovarian cancer cells in vitro via activating MEK/ERK pathway

AIM: E-cadherin is unusually highly expressed in most ovarian cancers. This study was designed to investigate the roles of E-cadherin in the carcinogenesis and progression of ovarian cancers. METHODS: Human ovarian adenocarcinoma cell line SKOV-3 was examined. E-cadherin gene CDH1 in SKOV-3 cells wa...

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Main Authors: Dong, Ling-ling, Liu, Lian, Ma, Chun-hong, Li, Ji-sheng, Du, Chao, XU, Shan, Han, Li-hui, Li, Li, Wang, Xiu-wen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010376/
https://ncbi.nlm.nih.gov/pubmed/22543706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.30
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