Lowering glucose level elevates [Ca(2+)](i) in hypothalamic arcuate nucleus NPY neurons through P/Q-type Ca(2+) channel activation and GSK3β inhibition

AIM: To identify the mechanisms underlying the elevation of intracellular Ca(2+) level ([Ca(2+)](i)) induced by lowering extracellular glucose in rat hypothalamic arcuate nucleus NPY neurons. METHODS: Primary cultures of hypothalamic arcuate nucleus (ARC) neurons were prepared from Sprague-Dawley ra...

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Detalhes bibliográficos
Main Authors: Chen, Yu, Zhou, Jun, Xie, Na, Huang, Chao, Zhang, Jun-qi, Hu, Zhuang-li, Ni, Lan, Jin, You, Wang, Fang, Chen, Jian-guo, Long, Li-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010362/
https://ncbi.nlm.nih.gov/pubmed/22504905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.17
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