Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation

AIM: To investigate the mechanisms underlying the anticancer effect of celecoxib on nasopharyngeal carcinoma (NPC). METHODS: NPC cell lines, HNE1 and CNE1-LMP1, were treated with various concentrations of celecoxib for 48 h. The antiproliferative effect of celecoxib was assessed using MTT assay. Bot...

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Main Authors: Liu, Dong-bo, Hu, Guang-yuan, Long, Guo-xian, Qiu, Hong, Mei, Qi, Hu, Guo-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010355/
https://ncbi.nlm.nih.gov/pubmed/22504904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.18
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