A carregar...

In vitro and in vivo investigation of dexibuprofen derivatives for CNS delivery

AIM: Dexibuprofen, the S(+)-isomer of ibuprofen, is an effective therapeutic agent for the treatment of neurodegenerative disorders. However, its clinical use is hampered by a limited brain distribution. The aim of this study was to design and synthesize brain-targeting dexibuprofen prodrugs and to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Xuan, Liu, Xing, Gong, Tao, Sun, Xun, Zhang, Zhi-rong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010340/
https://ncbi.nlm.nih.gov/pubmed/22301864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.144
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!