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Biology and Genetics of Prions Causing Neurodegeneration
Prions are proteins that acquire alternative conformations that become self-propagating. Transformation of proteins into prions is generally accompanied by an increase in β-sheet structure and a propensity to aggregate into oligomers. Some prions are beneficial and perform cellular functions, wherea...
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010318/ https://ncbi.nlm.nih.gov/pubmed/24274755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-110711-155524 |
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