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Voacamine Modulates the Sensitivity to Doxorubicin of Resistant Osteosarcoma and Melanoma Cells and Does Not Induce Toxicity in Normal Fibroblasts
[Image: see text] In previous studies it has been demonstrated that the plant alkaloid voacamine (1), used at noncytotoxic concentrations, enhanced the cytotoxicity of doxorubicin and exerted a chemosensitizing effect on cultured multidrug-resistant (MDR) U-2 OS-DX osteosarcoma cells. The in vitro i...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society and American
Society of Pharmacognosy
2014
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010292/ https://ncbi.nlm.nih.gov/pubmed/24720452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400950h |
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