Voacamine Modulates the Sensitivity to Doxorubicin of Resistant Osteosarcoma and Melanoma Cells and Does Not Induce Toxicity in Normal Fibroblasts

[Image: see text] In previous studies it has been demonstrated that the plant alkaloid voacamine (1), used at noncytotoxic concentrations, enhanced the cytotoxicity of doxorubicin and exerted a chemosensitizing effect on cultured multidrug-resistant (MDR) U-2 OS-DX osteosarcoma cells. The in vitro i...

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Xehetasun bibliografikoak
Egile Nagusiak: Condello, Maria, Cosentino, Dario, Corinti, Silvia, Di Felice, Gabriella, Multari, Giuseppina, Gallo, Francesca Romana, Arancia, Giuseppe, Meschini, Stefania
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society and American Society of Pharmacognosy 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010292/
https://ncbi.nlm.nih.gov/pubmed/24720452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400950h
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