Chromophore Photoreduction in Red Fluorescent Proteins Is Responsible for Bleaching and Phototoxicity

[Image: see text] Red fluorescent proteins (RFPs) are indispensable tools for deep-tissue imaging, fluorescence resonance energy transfer applications, and super-resolution microscopy. Using time-resolved optical spectroscopy this study investigated photoinduced dynamics of three RFPs, KillerRed, mR...

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Detalhes bibliográficos
Main Authors: Vegh, Russell B., Bravaya, Ksenia B., Bloch, Dmitry A., Bommarius, Andreas S., Tolbert, Laren M., Verkhovsky, Michael, Krylov, Anna I., Solntsev, Kyril M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010289/
https://ncbi.nlm.nih.gov/pubmed/24712386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp500919a
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