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Huperzine A derivative M3 protects PC12 cells against sodium nitroprusside-induced apoptosis

AIM: To investigate the effects of M3, a derivative of huperzine A, on the apoptosis induced by sodium nitroprusside (SNP) in PC12 cells. METHODS: Cell viability was detected using MTT method. Apoptosis was examined with annexin V/prodium iodide (PI) stain. The levels of reactive oxygen species (ROS...

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Detalhes bibliográficos
Main Authors: Ning, Na, Hu, Jin-feng, Yuan, Yu-he, Zhang, Xin-yuan, Dai, Jun-gui, Chen, Nai-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010272/
https://ncbi.nlm.nih.gov/pubmed/22120967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.147
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