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Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells

AIM: To investigate the effects of glucagon-like peptide-1 (GLP-1) on endothelial NO synthase (eNOS) in human umbilical vein endothelial cells (HUVECs), and elucidate whether GLP-1 receptor (GLP-1R) and GLP-1(9–36) are involved in these effects. METHODS: HUVECs were used. The activity of eNOS was me...

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Detalhes bibliográficos
Main Authors: Ding, Li, Zhang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010269/
https://ncbi.nlm.nih.gov/pubmed/22120969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.149
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