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FORMAL SYNTHESIS OF HAPALINDOLE O AND SYNTHETIC EFFORTS TOWARDS HAPALINDOLE K AND AMBIGUINE A

The formal synthesis of D,L-hapalindole O has been accomplished intercepting Natsume's total synthesis route. The intercepted substrate was synthesized in an overall 36% yield over ten-synthetic steps compared to Natsume's overall 1% yield over eighteen-synthetic steps. In addition, advanc...

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Detalhes bibliográficos
Main Authors: Rafferty, Ryan J., Williams, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010148/
https://ncbi.nlm.nih.gov/pubmed/24808627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3987/COM-12-S(N)3
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