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Synthetic Studies on the Ambiguine Family of Alkaloids: Construction of the ABCD Ring System

A racemic synthesis of the ABCD ring core of the ambiguines that preserves the tertiary alcohol has been accomplished in convergent synthesis in 10 synthetic steps, in an overall yield of 46% from commercially available 4-bromoindole and m-methylanisole.

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Detalhes bibliográficos
Main Authors: Rafferty, Ryan J., Williams, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079252/
https://ncbi.nlm.nih.gov/pubmed/21516192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.09.086
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