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Down regulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of Metastasis associated dapk1 in human cancers and cancer cells

DAPK1, a ca(+2)/calmodulin regulated serine/threonine kinase, is a major tumor suppressor, whose expression is lost in multiple tumor types. However, the mechanisms contributing to it are unclear. We have recently shown that CCAAT/Enhancer binding protein-β (C/EBP-β) is required for the basal and in...

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Библиографические подробности
Главные авторы: Gade, Padmaja, Singh, Ashish K., Roy, Sanjit K., Reddy, Sekhar P., Kalvakolanu, Dhananjaya V.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010141/
https://ncbi.nlm.nih.gov/pubmed/19521987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24493
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