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On the quantitation of an agonist with dual but opposing components of action: Application to vascular endothelial relaxation
In this communication we show that the same principle that underlies the use of the isobolograph for assessing agonist interactions also leads to a method for analyzing the opposing effects of a single agonist. This is the principle of dose equivalence whose application is illustrated here and appli...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010114/ https://ncbi.nlm.nih.gov/pubmed/21910983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.08.007 |
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