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Cocaine synergism with alpha agonists in rat aorta: computational analysis reveals an action beyond reuptake inhibition

BACKGROUND: Cocaine has long been known to increase blood pressure, but the degree and mechanism of vasoconstricting action remain poorly understood. Here we examine the interaction between cocaine and alpha-adrenoceptor agonists, with the action of reuptake inhibition minimized. METHODS: Cocaine wa...

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Detalhes bibliográficos
Main Authors: Lamarre, Neil S., Raffa, Robert B., Tallarida, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612562/
https://ncbi.nlm.nih.gov/pubmed/23270987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2012.11.020
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