Microsecond barrier-limited chain collapse observed by time-resolved FRET and SAXS

It is generally held that random coil polypeptide chains undergo a barrier-less continuous collapse when the solvent conditions are changed to favor the fully-folded native conformation. We test this hypothesis by probing intramolecular distance distributions during folding in one of the paradigms o...

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Hauptverfasser: Kathuria, Sagar V., Kayatekin, Can, Barrea, Raul, Kondrashkina, Elena, Graceffa, Rita, Guo, Liang, Nobrega, R. Paul, Chakravarthy, Srinivas, Matthews, C. Robert, Irving, Thomas C., Bilsel, Osman
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010103/
https://ncbi.nlm.nih.gov/pubmed/24607691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.02.020
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