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Crystal structure of vaccinia virus mRNA capping enzyme provides insights into the mechanism and evolution of the capping apparatus
Vaccinia virus capping enzyme is a heterodimer of D1 (844-aa) and D12 (287-aa) polypeptides that executes all three steps in m(7)GpppRNA synthesis. The D1 subunit comprises an N-terminal RNA triphosphatase (TPase)–guanylyltransferase (GTase) module and a C-terminal guanine-N7-methyltransferase (MTas...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010090/ https://ncbi.nlm.nih.gov/pubmed/24607143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.12.014 |
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