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CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives
AIM: To clarify whether CFTR is a molecular target of intestinal fluid secretion caused by the anthraquinone compounds from laxative herbal plants. METHODS: A cell-based fluorescent assay to measure I(−) influx through CFTR chloride channel. A short-circuit current assay to measure transcellular Cl(...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009961/ https://ncbi.nlm.nih.gov/pubmed/21602836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.46 |
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