Over-expression of aldehyde dehydrogenase-2 protects against H(2)O(2)-induced oxidative damage and apoptosis in peripheral blood mononuclear cells

AIM: To construct an eukaryotic expression vector containing the aldehyde dehydrogenase-2 (ALDH2) gene, and determine whether transfection with the ALDH2 gene can provide protection against hydrogen peroxide-induced oxidative damage, as well as attenuate apoptosis or cell death in human peripheral b...

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Bibliographic Details
Main Authors: Hu, Xiu-ying, Fang, Qin, Wang, Ji-shi, Xie, Jian-qiong, Chai, Bai-sheng, Li, Fang-qiong, Cui, Xin, Yang, Yuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009931/
https://ncbi.nlm.nih.gov/pubmed/21293477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.203
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