PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

Impairment of double-stranded DNA break (DSB) repair is essential to many cancers. However, while mutations in DSB repair proteins are common in hereditary cancers, mechanisms of impaired DSB repair in sporadic cancers remain incompletely understood. Here, we describe the first role for a long nonco...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Prensner, John R., Chen, Wei, Iyer, Matthew K., Cao, Qi, Ma, Teng, Han, Sumin, Sahu, Anirban, Malik, Rohit, Wilder-Romans, Kari, Navone, Nora, Logothetis, Christopher J., Araujo, John C., Pisters, Louis L., Tewari, Ashutosh K., Canman, Christine E., Knudsen, Karen E., Kitabayashi, Naoki, Rubin, Mark A., Demichelis, Francesca, Lawrence, Theodore S., Chinnaiyan, Arul M., Feng, Felix Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009928/
https://ncbi.nlm.nih.gov/pubmed/24473064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3159
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados