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HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods
The binding between the HIV-1 trans-activator of transcription (Tat) and p300/(CREB-binding protein)-associated factor (PCAF) bromodomain is a crucial step in the HIV-1 life cycle. However, the structure of the full length acetylated Tat bound to PCAF has not been yet determined experimentally. Acet...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009784/ https://ncbi.nlm.nih.gov/pubmed/24832227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology1020277 |
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