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A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G

APOBEC3G is the best known of several DNA cytosine deaminases that function to inhibit the replication of parasitic genetic elements including the lentivirus HIV. Several high-resolution structures of the APOBEC3G catalytic domain have been generated, but none reveal how this enzyme binds to substra...

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Bibliografische gegevens
Hoofdauteurs: Shindo, Keisuke, Li, Ming, Gross, Phillip J., Brown, William L., Harjes, Elena, Lu, Yongjian, Matsuo, Hiroshi, Harris, Reuben S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009770/
https://ncbi.nlm.nih.gov/pubmed/24832226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology1020260
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