Naofen promotes TNF-α-mediated apoptosis of hepatocytes by activating caspase-3 in lipopolysaccharide-treated rats

AIM: To investigate whether naofen is involved in tumor necrosis factor (TNF)-α-mediated apoptosis of hepatocytes induced by lipopolysaccharide (LPS). METHODS: In vivo, rats were treated with LPS or anti-TNF-α antibody, whereas in vitro, primary hepatocytes and Kupffer cells (KCs) were separately is...

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Detalhes bibliográficos
Main Authors: Fan, Jun-Hua, Feng, Guo-Gang, Huang, Lei, Tang, Guo-Duo, Jiang, Hai-Xing, Xu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009528/
https://ncbi.nlm.nih.gov/pubmed/24803807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i17.4963
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