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Functional Polymorphisms in Toll-like Receptor 4 Are Associated With Worse Outcome in Acute Ischemic Stroke Patients

Toll-like receptor-4 (TLR4) is important in neuroinflammation. Single nucleotide polymorphisms (SNPs) in TLR4, including 1063 A/G [Asp299Gly] and 1363 C/T [Thr399Ile], are associated with altered immune responses but their effect on acute ischemic stroke (AIS) outcome is unknown. We collected demogr...

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Detalhes bibliográficos
Main Authors: Weinstein, Jonathan R., Schulze, Juliane, Lee, Richard V., Phillips, Hunter, Zierath, Dannielle, Tanzi, Patricia, Shibata, Dean, Cain, Kevin C., Becker, Kyra J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009512/
https://ncbi.nlm.nih.gov/pubmed/24784586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000140
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