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Severe stroke induces long lasting alterations of HMGB-1

BACKGROUND AND PURPOSE: The signals that initiate the post-stroke inflammatory response are unknown. High mobility group box (HMGB) 1 protein is a nuclear protein that is passively released from necrotic tissue and is able to activate leukocytes, which in turn secrete HMGB1. HMGB1 is also able to ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schulze, Juliane, Zierath, Dannielle, Tanzi, Patricia, Cain, Kevin, Shibata, Dean, Dressel, Alexander, Becker, Kyra
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530419/
https://ncbi.nlm.nih.gov/pubmed/23204053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.112.676072
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