IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression.

We have generated transgenic mouse lines that carry one of three different constructs in which the murine N-myc gene is expressed under the control of the immunoglobulin heavy chain transcriptional enhancer element (E mu-N-myc genes). High-level expression of the E mu-N-myc transgenes occurred in ly...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Dildrop, R, Ma, A, Zimmerman, K, Hsu, E, Tesfaye, A, DePinho, R, Alt, F W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2501083/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03482.x
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