Differential Transcript Profiles of MHC Class Ib(Qa-1, Qa-2, and Qa-10) and Aire Genes during the Ontogeny of Thymus and Other Tissues

Qa-2 and Qa-1 are murine nonclassical MHC class I molecules involved in the modulation of immune responses by interacting with T CD8(+) and NK cell inhibitory receptors. During thymic education, the Aire gene imposes the expression of thousands of tissue-related antigens in the thymic medulla, permi...

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Hlavní autoři: Melo-Lima, Breno Luiz, Evangelista, Adriane Feijó, de Magalhães, Danielle Aparecida Rosa, Passos, Geraldo Aleixo, Moreau, Philippe, Donadi, Eduardo Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009201/
https://ncbi.nlm.nih.gov/pubmed/24829926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/159247
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