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Role of phosphodiesterase inhibitor Ibudilast in morphine-induced hippocampal injury

BACKGROUND: Opioid drugs are used in the treatment of acute post-surgical pain and chronic pain, such as those associated with cancer. Opioid used is associated with complications such as analgesic tolerance, dependence and opioid abuse. The molecular mechanisms of unwanted opioid responses are vari...

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Detalhes bibliográficos
Main Authors: Zhaleh, Mohsen, Panahi, Marzieh, Ghafurian Broujerdnia, Mehri, Ghorbani, Rostam, Ahmadi Angali, Kambiz, Saki, Ghasem
Formato: Artigo
Idioma:Inglês
Publicado em: Kermanshah University of Medical Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009172/
https://ncbi.nlm.nih.gov/pubmed/24121451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5249/jivr.v6i2.497
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