Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction

BACKGROUND: Left ventricular (LV) hypertrophy in aortic stenosis (AS) is characterized by reduced myocardial perfusion reserve due to coronary microvascular dysfunction. However, whether this hypoperfusion leads to tissue deoxygenation is unknown. We aimed to assess myocardial oxygenation in severe...

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Autori principali: Mahmod, Masliza, Francis, Jane M, Pal, Nikhil, Lewis, Andrew, Dass, Sairia, De Silva, Ravi, Petrou, Mario, Sayeed, Rana, Westaby, Stephen, Robson, Matthew D, Ashrafian, Houman, Neubauer, Stefan, Karamitsos, Theodoros D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009072/
https://ncbi.nlm.nih.gov/pubmed/24779370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1532-429X-16-29
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