Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction

BACKGROUND: Left ventricular (LV) hypertrophy in aortic stenosis (AS) is characterized by reduced myocardial perfusion reserve due to coronary microvascular dysfunction. However, whether this hypoperfusion leads to tissue deoxygenation is unknown. We aimed to assess myocardial oxygenation in severe...

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Hlavní autoři: Mahmod, Masliza, Francis, Jane M, Pal, Nikhil, Lewis, Andrew, Dass, Sairia, De Silva, Ravi, Petrou, Mario, Sayeed, Rana, Westaby, Stephen, Robson, Matthew D, Ashrafian, Houman, Neubauer, Stefan, Karamitsos, Theodoros D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009072/
https://ncbi.nlm.nih.gov/pubmed/24779370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1532-429X-16-29
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