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Use of Bru-Seq and BruChase-Seq for genome-wide assessment of the synthesis and stability of RNA
Gene expression studies commonly examine total cellular RNA, which only provides information about its steady-state pool of RNA. It remains unclear whether differences in the steady-state reflects variable rates of transcription or RNA degradation. To specifically monitor RNA synthesis and degradati...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009065/ https://ncbi.nlm.nih.gov/pubmed/23973811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.08.015 |
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