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Investigation of an APP protective mutation (A673T) in a North American case-control sample of late-onset Alzheimer’s disease

A rare amyloid precursor protein (APP) gene variant, A673T (rs63750847) was recently reported to protect against Alzheimer’s disease (AD) and age-related cognitive decline among Icelanders and the same rare variant was observed also in Finnish, Norwegian, and Swedish populations. We investigated thi...

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Bibliografski detalji
Glavni autori: Bamne, Mikhil N., Demirci, F. Yesim, Berman, Sarah, Snitz, Beth E., Rosenthal, Samantha L., Wang, Xingbin, Lopez, Oscar L., Kamboh, M. Ilyas
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009010/
https://ncbi.nlm.nih.gov/pubmed/24529499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.020
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