Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a TRPP2 (polycystin-2)-dependent manner

BACKGROUND AND PURPOSE: Identifying and characterizing potential new therapeutic agents to target cell proliferation may provide improved treatments for neoplastic disorders such as cancer and polycystic diseases. EXPERIMENTAL APPROACH: We used the simple, tractable biomedical model Dictyostelium to...

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Detalhes bibliográficos
Main Authors: Waheed, A, Ludtmann, M H R, Pakes, N, Robery, S, Kuspa, A, Dinh, C, Baines, D, Williams, R S B, Carew, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Themed Section: The Pharmacology of Trp Channels
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009007/
https://ncbi.nlm.nih.gov/pubmed/24116661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12443
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