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Inhibition of farnesyl pyrophosphate synthase prevents angiotensin II-induced cardiac fibrosis in vitro

Farnesyl pyrophosphate synthase (FPPS)-catalysed isoprenoid intermediates are important for the activation of Ras homologue gene family, member A (RhoA) in angiotensin (Ang) II-induced cardiac fibrosis. This study was designed to investigate the specific role of FPPS in the development of cardiac fi...

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Main Authors: Li, Z, Bi, X, Wang, M, Zhang, J, Song, J, Shen, X, Han, J, Fu, G, Ye, Y
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008988/
https://ncbi.nlm.nih.gov/pubmed/24527834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12282
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