Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers

X-ray free-electron laser (XFEL) sources enable the use of crystallography to solve three-dimensional macromolecular structures under native conditions and free from radiation damage. Results to date, however, have been limited by the challenge of deriving accurate Bragg intensities from a heterogen...

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Main Authors: Hattne, Johan, Echols, Nathaniel, Tran, Rosalie, Kern, Jan, Gildea, Richard J., Brewster, Aaron S., Alonso-Mori, Roberto, Glöckner, Carina, Hellmich, Julia, Laksmono, Hartawan, Sierra, Raymond G., Lassalle-Kaiser, Benedikt, Lampe, Alyssa, Han, Guangye, Gul, Sheraz, DiFiore, Dörte, Milathianaki, Despina, Fry, Alan R., Miahnahri, Alan, White, William E., Schafer, Donald W., Seibert, M. Marvin, Koglin, Jason E., Sokaras, Dimosthenis, Weng, Tsu-Chien, Sellberg, Jonas, Latimer, Matthew J., Glatzel, Pieter, Zwart, Petrus H., Grosse-Kunstleve, Ralf W., Bogan, Michael J., Messerschmidt, Marc, Williams, Garth J., Boutet, Sébastien, Messinger, Johannes, Zouni, Athina, Yano, Junko, Bergmann, Uwe, Yachandra, Vittal K., Adams, Paul D., Sauter, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008696/
https://ncbi.nlm.nih.gov/pubmed/24633409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2887
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