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Toll-Like Receptor (TLR)-1/2 Triggering of Multiple Myeloma Cells Modulates Their Adhesion to Bone Marrow Stromal Cells and Enhances Bortezomib-Induced Apoptosis

In multiple myeloma (MM), the malignant plasma cells usually localize to the bone marrow where they develop drug resistance due to adhesion to stromal cells and various environmental signals. Hence, modulation of this interaction is expected to influence drug sensitivity of MM cells. Toll-like recep...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abdi, Jahangir, Mutis, Tuna, Garssen, Johan, Redegeld, Frank A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008602/
https://ncbi.nlm.nih.gov/pubmed/24794258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096608
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