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Protein Kinase C θ Regulates the Phenotype of Murine CD4(+) Th17 Cells

Protein kinase C θ (PKCθ) is involved in signaling downstream of the T cell antigen receptor (TCR) and is important for shaping effector T cell functions and inflammatory disease development. Acquisition of Th1-like effector features by Th17 cells has been linked to increased pathogenic potential. H...

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Main Authors: Wachowicz, Katarzyna, Hermann-Kleiter, Natascha, Meisel, Marlies, Siegmund, Kerstin, Thuille, Nikolaus, Baier, Gottfried
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008503/
https://ncbi.nlm.nih.gov/pubmed/24788550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096401
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