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N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl.

The two major forms of the c-abl gene differ from their activated counterpart, the v-abl oncogene of the Abelson murine leukemia virus by the replacement of their N-terminal sequences with viral gag sequences. Overexpression of p150c-abl type IV in a retroviral vector similar to Abelson virus does n...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Jackson, P, Baltimore, D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC400826/
https://ncbi.nlm.nih.gov/pubmed/2542016
Etiketler: Etiketle
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