Phase II Trial of Pyrazoloacridine in Children With Solid Tumors: A Pediatric Oncology Group Phase II Study

PURPOSE: Pyrazoloacridine (PZA), a rationally synthesized deoxyribonucleic acid (DNA) binding agent that preferentially inhibits ribonucleic acid rather than DNA synthesis, is active against hypoxic and noncycling tumor cells and has greater in vitro activity against a broad range of human solid tum...

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Bibliografiska uppgifter
Huvudupphovsmän: Berg, Stacey L., Blaney, Susan M., Sullivan, James, Bernstein, Mark, Dubowy, Ronald, Harris, Michael B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2000
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008246/
https://ncbi.nlm.nih.gov/pubmed/11132217
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