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Yeast upstream activator protein GCN4 can stimulate transcription when its binding site replaces the TATA element.
We replaced the required TATA element of a yeast gal-his3 promoter by a binding site for GCN4, a protein that normally activates transcription when bound upstream of a TATA element. Surprisingly, GCN4 efficiently activates his3 transcription from wild-type initiation sites, though in a pattern assoc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC400798/ https://ncbi.nlm.nih.gov/pubmed/2653813 |
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