Development of Fluorescent Ligands for the Human 5-HT(1A) Receptor

[Image: see text] In this work, we report the design and synthesis of a set of fluorescent probes targeting the human 5-HT(1A) receptor (h5-HT(1A)R). Among the synthesized compounds, derivative 4 deserves special attention as being a high-affinity ligand (K(i) = 2 nM) with good fluorescent propertie...

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Main Authors: Alonso, Dulce, Vázquez-Villa, Henar, Gamo, Ana M., Martínez-Esperón, María F., Tortosa, Mariola, Viso, Alma, Fernández de la Pradilla, Roberto, Junquera, Elena, Aicart, Emilio, Martín-Fontecha, Mar, Benhamú, Bellinda, López-Rodríguez, María L., Ortega-Gutiérrez, Silvia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2010
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007967/
https://ncbi.nlm.nih.gov/pubmed/24900203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100053y
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