Synthesis and Biological Evaluation of Muraymycin Analogues Active against Anti-Drug-Resistant Bacteria

[Image: see text] Muraymycin analogues with a lipophilic substituent were synthesized using an Ugi four-component assemblage. This approach provides ready access to a range of analogues simply by altering the aldehyde component. The impact of the lipophilic substituent on the antibacterial activity...

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Main Authors: Tanino, Tetsuya, Ichikawa, Satoshi, Al-Dabbagh, Bayan, Bouhss, Ahmed, Oyama, Hiroshi, Matsuda, Akira
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2010
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007965/
https://ncbi.nlm.nih.gov/pubmed/24900205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100057z
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