Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis

HAX1 was identified as the gene responsible for the autosomal recessive type of severe congenital neutropenia. However, the connection between mutations in the HAX1 gene and defective granulopoiesis in this disease has remained unclear, mainly due to the lack of a useful experimental model for this...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Morishima, Tatsuya, Watanabe, Ken-ichiro, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsugu, Hiramatsu, Hidefumi, Saito, Megumu K., Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutoshi, Heike, Toshio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Ferrata Storti Foundation 2014
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007926/
https://ncbi.nlm.nih.gov/pubmed/23975175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.083873
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