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Efficient Radiosynthesis of 2-[(18)F]Fluoroadenosine: A New Route to 2-[(18)F]Fluoropurine Nucleosides

[Image: see text] An efficient method to incorporate the fluorine-18 radionuclide in 2-nitropurine-based nucleosides was developed. The nucleophilic radiofluorination of the labeling precursor with [(18)F]KF under aminopolyether-mediated conditions (Kryptofix 2.2.2/K(2)CO(3)) followed by deprotectio...

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Detalhes bibliográficos
Main Authors: Marchand, Patrice, Lorilleux, Christophe, Gilbert, Gwénaëlle, Gourand, Fabienne, Sobrio, Franck, Peyronnet, Damien, Dhilly, Martine, Barré, Louisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007834/
https://ncbi.nlm.nih.gov/pubmed/24900201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100055m
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