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Withagulatin A inhibits hepatic stellate cell viability and procollagen I production through Akt and Smad signaling pathways

AIM: To investigate the effects of the natural product Withagulatin A on hepatic stellate cell (HSC) viability and type I procollagen production. The potential mechanism underlying the pharmacological actions was also explored. METHODS: The effect of Withagulatin A on cell viability was evaluated in...

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Detalhes bibliográficos
Main Authors: Liu, Qiong, Chen, Jing, Wang, Xu, Yu, Liang, Hu, Li-hong, Shen, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007817/
https://ncbi.nlm.nih.gov/pubmed/20644552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.72
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