Leukamenin F suppresses liver fibrogenesis by inhibiting both hepatic stellate cell proliferation and extracellular matrix production

AIM: To investigate the inhibitory effect of the natural product Leukamenin F on liver fibrosis and explore its potential underlying mechanisms. METHODS: Carbon tetrachloride (CCl(4))-treated mouse model in vivo and in hepatic stellate cells (HSC) in vitro were used. The effect on CCl(4)-induced liv...

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Detalhes bibliográficos
Main Authors: Liu, Qiong, Wang, Xu, Zhang, Yu, Li, Chen-jing, Hu, Li-hong, Shen, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007723/
https://ncbi.nlm.nih.gov/pubmed/20562900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.64
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