Imatinib plasma trough concentration and its correlation with characteristics and response in Chinese CML patients

AIM: To investigate the pharmacokinetics of imatinib in Chinese chronic myelogenous leukemia (CML) patients. METHODS: Fourty-six naïve Chinese CML patients treated with imatinib (400 and 600 mg daily, n=36 and 10, respectively) were recruited. The correlations of imatinib (400 mg) trough plasma conc...

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Detalhes bibliográficos
Main Authors: Li, Qiu-bai, Chen, Chao, Chen, Zhi-chao, Wang, Hong-xiang, Wu, Yan-lin, You, Yong, Zou, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007812/
https://ncbi.nlm.nih.gov/pubmed/20644548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.79
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