Protective effects of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of MEK/ERK and PI3K/Akt pathways in neutrophils

AIM: To investigate whether luteolin, the major polyphenolic components of Lonicera japonica, has beneficial effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) and to determine whether the protective mechanism involves anti-inflammatory effects on neutrophils. METHODS: ALI was...

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Bibliografiske detaljer
Main Authors: Lee, Jen-pei, Li, Yi-ching, Chen, Hung-yi, Lin, Ruey-hseng, Huang, Shiang-suo, Chen, Hui-ling, Kuan, Pai-chuan, Liao, Mao-fang, Chen, Chun-jung, Kuan, Yu-hsiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007725/
https://ncbi.nlm.nih.gov/pubmed/20562902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.62
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